INNOVATIVE CONCEPTS IN FORMULATION DESIGN OF NOVEL PHARMACEUTICALS

M. Selva Vignesh*, Dr. G. Selvi, P. Nirmal, S. Sathyanarayanan, S. Suresh Kannan and V. Praveen Kumar

ABSTRACT

Innovation plays a crucial role in the design of pharmaceutical formulations, as it enables the development of more effective and patient-friendly drug delivery systems. This article explores new concepts and strategies in formulation design, with a focus on advancements in nanotechnology, bioavailability enhancement, and personalized medicine. By integrating material science, pharmacokinetics, and biopharmaceutical analysis, studies conducted in past years demonstrate thatthe effectiveness of cutting-edge techniques such as Nanotechnology, Lipid-based Formulations, Microfluidics, Smart Drug Delivery Systems, Biocompatible polymers, Pro drug Technology, Continuous Manufacturing, Combination Therapy, Computer modeling drug design, 3D-printed dosage forms, SBDD (Secondary, structure- Based design), Ligand based drug design (LBDD), and targeted delivery systems. These innovations have the potential to revolutionize pharmaceutical development, offering safer and more efficient therapeutic solutions.

Keywords: Drug design, Nanotechnology, Computer modeling drug design, 3D-printed dosage forms, SBDD (Secondary, structure- Based design), Ligand based drug design (LBDD), and targeted delivery systems.