FORMULATION AND EVALUATION OF ANTIFUNGAL CREAM SHAMPOO USING KETOCONAZOLE

Dr. Shahid Mohammed*, Syeda Fouzia Mohammedi and Reem Ahmeed Ali

ABSTRACT

Shampoo is a hair care product that is use for cleansing of hair and nourishing them and making them protective
against outer environment. It removes oil, dirt, dandruff and other particles. So basically, ketoconazole shampoo
helps for the treatment of dandruff and fungus in the scalp which is also called as seborrhoeic dermatitis. So, we
have made 3 formulation and optimized the composition and compared with the marketed formulation (dan free)
shampoo which is marketed by Cipla. With comparison with that product our product shows similar results
obtained by marketed product. So we can say our product got satisfactory results and also we have compared the
results obtained with available parameters, Basically the ketoconazole shampoo we examined by checking its PH,
viscosity, appearance, foam ability and foam stability, surface tension measurement, stability studies, Wetting time,
percentage of solid content etc. and the shampoo has been formulated using ingredients like ketoconazole [API],
PVP, Sodium metabisulfite, Sodium lauryl sulphate, Stearic acid, Methyl cellulose, EDTA, sodium hydroxide,
amaranth colour and water. More specifically the product we formulated is sulphate free. Hence the prepared
antifungal shampoo suits human scalp and can be therapeutic to alternative fungal infections.

Keywords: Antifungal, ketoconazole, antifungal shampoo, fungal infections.