INVERSION OF BRONCHIAL ANATOMY AND LUNG SEGMENTS IN KARTAGENER SYNDROME: A RETROSPECTIVE ANALYSIS OF FIVE SITUS INVERSUS CASES AND THEIR CLINICAL IMPLICATIONS

Trilok Chand*, Rakesh Kumar Gupta, Sivan Pillay Azhagappan and Fathimath Nihana Abdul Mubaruck

ABSTRACT

Kartagener’s Syndrome (KS), a subset of primary ciliary dyskinesia, is characterized by a triad of chronic sinusitis, bronchiectasis, and situs inversus. This retrospective analysis examines cases of five patients diagnosed with situs inversus as part of KS, focusing on the inversion of bronchial anatomy and lung segments. Detailed imaging assessments revealed a consistent mirroring of bronchial tree structures and lung segments, necessitating a tailored approach for diagnostic and procedural strategies. The findings highlight the importance of recognizing altered anatomical landmarks to prevent procedural complications and improve patient outcomes. Furthermore, this article discusses how awareness of these unique presentations can inform targeted therapies and surgical planning, ultimately enhancing the quality of care for patients with KS. Knowledge of these clinical implications is essential for healthcare providers managing this rare congenital disorder.

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