EXPLORING THE DYNAMIC CHEMISTRY AND THERAPEUTIC POTENTIAL OF PYRIMIDINE DERIVATIVES

Pooja Patle*, Shweta Dhole, Sakshi Mude, P. P. Katolkar and J. R. Baheti

ABSTRACT

Similar to pyridine, pyrimidine is an aromatic heterocyclic chemical molecule. The "Principal Synthesis" method, which involves cyclizing beta-carbonyl molecules with N-C-N compounds, is commonly used to synthesis pyrimidines. Both the Biginelli and Pinner reactions can be used to produce pyrimidine. A class of heterocyclic scaffolds known as pyrimidine and its fused pyrimidine derivatives has a wide range of biological and pharmacological actions, including antibacterial, antiviral, antifungal, anxiolytic, anticancer, and antioxidant properties.

Keywords: Pyrimidine, Heterocyclic, Synthesis, Pharmacological, Anticancer.