SELECTED INDONESIAN MEDICINAL PLANTS FOR THE MANAGEMENT OF ALZHEIMER'S DISEASE – A REVIEW

Ardyan Johanka, Adilah Hasan, Alfrida Riyani Pratiwi, Alvina Nurhaliza, Dwi Rismaningrum, Imelda Rosalinda, Jihan Safitri, Nabila Malihatul 'Ain Al-latifah, Nur Halimatus Sa'diyah, Nurul Bariyatut Thohirotun Nisaa, Thitanyana Wangsa, Verani, Wati, Windi Kartika Laela, Wiwin Sri Intan, Maulana Yusuf Alkandahri*

ABSTRACT

Psychological issues significantly exacerbate numerous neurodegenerative disorders, including Alzheimer's disease. Alzheimer's disease, the most common form of dementia, affects health and well-being. Researchers are currently searching for novel neuroprotective compound candidates derived from natural ingredients and empirically demonstrated to have pharmacological effects on Alzheimer's disease. Researchers are implementing this as a substitute for Alzheimer's disease medications, which currently have numerous hazardous adverse effects. Several native Indonesian medicinal plants, such as Zingiber officinale, Andrographis paniculata, Apium graveolens, Kaempferia galanga, Psidium guajava, Curcuma longa, and Morinda citrifolia, have been shown to protect neurons in different ways by scientists. Consequently, this review article explores the potential of numerous indigenous Indonesian medicinal plants that exhibit pharmacological effects on Alzheimer's disease.

Keywords: Alzheimer’s disease, Zingiber officinale, Andrographis paniculata, Apium graveolens, Kaempferia galanga, Psidium guajava, Curcuma longa, Morinda citrifolia.