EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

FORMULATION & EVALUATION OF TRANSDERMAL PATCH OF ACETOHEXAMIDE

Ganju Eisha* and Ganju Kuldeep

ABSTRACT

The aim of the present investigation was to prepare acetohexamide transdermal patches by solvent casting technique using the HPMC and PVP. The systems were evaluated for various in- vitro parameters (Thickness, Folding endurance, Moisture content, Moisture uptake, Flatness, Water vapor transmission rate etc). In- vitro permeation studies were performed by using Franz diffusion cells. Variations in drug permeation profile were observed among various formulations. From all the formulations, formulation P3 was selected as the best formulation and formulation was stable for period of 90 days stability study.

Keywords: Transdermal drug delivery, Matrix patch, Membrane controlled Patch, acetohexamide, HPMC, PVP, In vitro skin permeation studies.


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SJIF Impact Factor: 7.065

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia

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