A LABORATORY STUDY OF BLOOD D-DIMER IN LARYNGEAL CANCER PATIENTS BEFORE AND AFTER SURGERY

Dr. Moayad Kheirbek*, Mostafa Ibrahim and Faisal Radwan

ABSTRACT

Laryngeal cancer is the second most common head and neck cancer around the world, and the most common site of carcinoma is in the upper respiratory and digestive tracts. The research aimed to study the laboratory parameters of D-Dimer, by studying the difference in D-Dimer values for patients before and after surgery, and then comparing these values with a control group. The research was conducted on all patients who had been diagnosed with laryngeal cancer from the Department of Otorhinolaryngology and its Surgery at Tishreen University Hospital in Latakia, and who had undergone surgery for this tumor, after obtaining informed consent. A prospective study was conducted, and the number of patients reached (30) patients. A search form was organized for patients. The research results showed that D-Dimer values in laryngeal cancer patients increase after surgery compared to their values before surgery, and that there is a statistically significant difference between the D-Dimer values in laryngeal cancer patients before and after surgery and the control group. The research recommends that D-Dimer can be used with other tests to develop new diagnostic tools for laryngeal cancer, and this may help diagnose cancer early, and then treatment will be more effective, and that D-Dimer levels can be monitored after treatment to measure the patient’s response to treatment, and this It may help determine if treatment is effective and when treatment adjustments may be needed.

Keywords: D-Dimer, laryngeal cancer, patients.