COMPARATIVE ANALYSIS OF CHANDIPURA VIRUS AND NIPAH VIRUS

Princy R.* and Nebin Sajeer

ABSTRACT

Viral illnesses represent substantial public health issues worldwide, with some pathogens having distinct regional effects. This review compares Chandipura virus (CHPV) with Nipah virus (NiV), examining their virology, epidemiology, clinical symptoms, pathogenesis, transmission dynamics, diagnosis, prevention, and control. CHPV, a member of the Rhabdoviridae family, mostly affects parts of India, causing acute encephalitis with significant fatality rates. NiV, a member of the Paramyxoviridae family, has a greater geographic distribution, including Southeast Asia, and is associated with severe respiratory and neurological symptoms. The review highlights variations and similarities in the viruses' illness mechanisms, transmission routes, and public health implications. It also outlines research gaps and avenues for further exploration, such as vaccine development and antiviral medicines. The potential for both viruses to generate endemic or pandemic outbreaks highlights the importance of global planning and response strategies. Understanding these viruses' properties and effects is critical for developing effective management and prevention methods.

Keywords: Chandipura virus, Nipah virus, comparative analysis, virology, epidemiology, clinical manifestations, pathophysiology, transmission, diagnosis, prevention, global health preparedness.