USE OF LONGITUDINAL MYOCARDIAL DEFORMATION TO ASSESS THE EFFECTIVENESS OF REPERFUSION IN ACUTE CORONARY SYNDROME WITH STSEGMENT ELEVATION

Atamuratov B. R.*, Fozilov Kh. G., Abdullaeva S. Ya., Bekmetova F. M. and Yuldashov B. A.

ABSTRACT

Currently, acute myocardial infarction continues to be the leading cause of cardiovascular morbidity and mortality
worldwide. It can be said that the rapid restoration of blood flow in the coronary artery associated with a heart
attack is a key factor determining the size of a heart attack, maintaining myocardial viability and improving clinical
outcomes. Objective of the study: Longitudinal myocardial deformity was assessed in groups of patients with
acute coronary syndrome who underwent primary thrombolysis, primary percutaneous coronary intervention (PCI)
and salvage PCI. Materials and Methods: The study was conducted on the basis of the Republican Specialized
Scientific and Practical Medical Center of Cardiology and included 200 patients with acute coronary syndrome
with ST elevation. Patients were divided into 3 groups depending on the method of reperfusion: primary
thrombolysis (62 patients), primary PCI (106 patients) and salvage PCI performed after unsuccessful thrombolysis
(32 patients). All patients received standard therapy, including acetylsalicylic acid, ticagrelor, enoxaparin, betablockers
and ACE inhibitors. Results: Three main groups were identified, which did not differ from each other in
terms of basic demographic characteristics. However, when studying the results of coronary angiography, it is
necessary to note a significant predominance of two- and multivessel coronary artery lesions in the primary PCI
group.

Keywords: Acute coronary syndrome (ACS), percutaneous coronary intervention (PCI), high-tech treatment methods.