AN OBSERVATIONAL STUDY ON CLINICAL SAFETY AND EFFICACY OF MEDICATIONS USED IN THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA

*Beesam Sai Manisha, Balla Sheetal, Gandham Chaitanya, Dr. Naveen Kumar, Dr. Manne Venu and Dr. Kaveti Balaji

ABSTRACT

Background: BPH is a condition that occurs in males, where there is an enlargement of the prostate gland and is non-cancerous. This enlargement will exert pressure on the urethra, resulting in various urinary symptoms. BPH is also known as a “prostate gland enlargement that is not cancerous”. Alpha blockers and inhibitors of the 5-alpha reeducates are the effective medications which are applied to treat BPH. Methods: This is an observational study on clinical safety and efficacy of medications used in the treatment of BPH which includes case reports of 70 individuals that was carried out for duration of six months. This study was conducted by surveying patients in both the IP and OP Departments. Results: In a research study conducted which includes 70 male patients; the patients were split into 6 classes based on age criteria: 40-50, 50-60, 60-70, 70-80, 80-90, and 90-100. In that the majority of the cases were seen in the patients[19] of age group 80-90, followed by[14] patients within the age range of 70-80, followed by same count of patients[13] fall within the age groups of 60-70 and 50-60, followed by[7] patients were seen in the age group of 40-50 and a least number of patients[4] were seen in the category of 90-100. The patients with all the age groups were prescribed with the medications of both combination and individual therapy. So, the total number of patients[55] who have received the combination therapy had shown their effectiveness in enhancing the patient’s quality of life. Conclusion: From the study which was conducted we can summarize that those patients who had received the combination therapy (78.01%) had shown their effectiveness in reducing the symptoms of BPH and enhances the quality of life for the patient when compared to individual therapy (21.39%).

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