THE ASSOCIATION BETWEEN PLACENTA PREVIA AND PLACENTA INCRETA AND LEUKOCYTE AND PLATELET INDICES

*Raghdah Aassy, Ahmad Yousef and Thawra Naiseh

ABSTRACT

Aim: Despite medical advances, rising awareness, and satisfactory care facilities, placenta previa (PP) remains a challenging clinical entity due to the risk of excessive obstetric hemorrhage. Etiological concerns gave way to life-saving concerns about the prediction of maternal outcomes due to hemorrhage. The study aims to detect early predictive indicators of defective placenta previa and its associated adhesion abnormalities such as insertion using simple and available laboratory variables related to leukocytes and platelets in patients of Tishreen University Hospital to find a scanning test through which the risk of ablation and insertion can be predicted. Materials and Methods: Forty pregnant patients diagnosed with PP and 50 controls were recruited for this case report study. Platelet and leukocyte indices were compared between the two groups. Results: The groups were similar with regard to age distribution (31.56±4.9 years [mean ± SD] in the PP group and 29.08±5.6 years in controls), body mass index (BMI) (64.25±5.3 kg/m2 in the PP group and 61.49±7.3 kg/m2 in controls), and most characteristics of the obstetric history. Total leukocyte count, neutrophil count, and neutrophil-to-lymphocyte ratio were significantly higher in the PP group. Mean platelet volume (MPV) and large platelet cell ratio (P-LCR) values were significantly lower in the PP group as compared to controls, with regard to third trimester values. However, patients who were diagnosed postnatal with placenta percreta had lower MPV and P-LCR values than other patients with PP. There were no statistically significant differences between the two groups as far as first trimester values were concerned. Conclusion: Platelet and leukocyte indices in the third trimester of pregnancy may be valuable predictors of placenta previa and placenta percreta. More comprehensive studies are needed to address this issue.

Keywords: leukocyte indices, placenta percreta, placenta previa, platelet indices, Prediction.