THE ALTERATION IN UREA AND CREATININE IN PATIENTS WITH RENAL FAILURE UNDERGOING HEMODIALYSIS

Inas Ali-Algheriani* and Ghada Algblawi

ABSTRACT

Background: The prevalence of end-stage kidney disease (ESKD) is on the rise globally, and Libya is no exception, as it has witnessed a significant increase in recent decades. Aim of study: The aim of this study was to examine the levels of urea and creatinine in chronic kidney disease (CKD) patients undergoing hemodialysis. Methodology: For this study, 60 hemodialysis patients from Subrata Kidney Centre were recruited between March and April 2021. Venous blood samples were collected from each patient, and the serum was separated to determine the levels of creatinine and urea before and after dialysis. Result: The results show that the levels of creatinine and urea were higher in both males and females before dialysis. However, after dialysis, the levels were significantly reduced (p<0.05). Conclusion: In conclusion, the study suggests that hemodialysis is a useful approach to reducing the levels of urea and creatinine, thereby improving the clinical condition of patients.

Keywords: Renal failure, Hemodialysis, Blood serum, Creatinine and urea profiles.