PRIMARY VARICOSE VEINS PATHOGENESIS AND TREATMENT MODALITIES – A REVIEW

Vedant Sunil Borode*, Jayesh Sandip Sawarkar and Anand Shriram Baley

ABSTRACT

Valvular incompetence and reflux are seem to be as common features of primary varicose veins, and have long been thought to be their cause. Recent studies and information however, suggests that changes in the vein wall may precede valvular dysfunction. Age, sex, pregnancy, and a positive family history are significant risk factors for the development of varicose veins. Varicose veins have less total elastin than non-varicose veins do; overall collagen content variations are unclear. Every 1 in 4 persons suffers this condition and it goes unnoticed until the condition worsens so early precautions and preventive measures are needed. New researches are being done on bringing the medical and ayurvedic treatments on a board for treating varicose veins. New advancements discussing the personalised treatment and patient centralised curative methods are being studied. Increasing incidences of varicose veins demand less surgical and invasive modes of treatment, so developing novel medications for treatment is a call of hour and researches are made in the same direction.

Keywords: Valvular incompetence, reflux, valvular dysfunction, family history, collagen content.