ANTI ULCER ACTIVITY OF ETHANOLIC EXTRACT OF DIOSPYROS PANICULATA

Mithun K. Sebastian* and Shan P. Mohammed

ABSTRACT

This study was conducted to evaluate the anti ulcer activity of the ethanolic extract of Diospyros Paniculata(bark). The study was performed by doing the Indomethacin induced ulcer in rats and ethanol induced ulcers in rat. The ulcer index is calculated and also the Percentage protection. Results obtained in both of these models show significant Anti ulcer activity with P < 0.01. Findings obtained indicate that the Diospyros Paniculata is having significant anti ulcer activity.

Keywords: Diospyros Paniculata, Anti ulcer, In vivo, Indomethacin, ethanol.