WHITE ANALYTICAL CHEMISTRY: A COMPREHENSIVE APPROACH FOR INTEGRATING SUSTAINABLE DEVELOPMENT PRINCIPLES IN ANALYTICAL CHEMISTRY

Gumte Vaishnavi, Bathula Neha, Divya Pingili, Archana Awasthi* and Sridevi Pingali

ABSTRACT

White Analytical Chemistry (WAC) is introduced as an evolution of Green Analytical Chemistry (GAC). The 12
WAC principles were introduced to replace the current 12 GAC principles. The WAC improves the environmental
aspects of GAC by incorporating extra critical factors that influence method quality, encompassing analytical (red)
and practical (blue) dimensions. Like the RGB color model, the combination of red, green, and blue creates an
appearance of white. A WAC method illustrates the integration and balance of analytical, ecological, and practical
characteristics. The notion of whiteness can be evaluated by examining certain concepts, providing an appropriate
standard for comparison, and identifying the best suitable methodology. The WAC aligns more closely with
sustainable development principles due to its comprehensive approach, which seeks to attain a balance that does
not sacrifice functionality for environmental considerations. This review overviews recent advances, including the
potential use of a hybrid approach. By integrating WAC principles with experimental design, offering a costeffective,
environmentally sustainable, and user-friendly alternative for developing analytical methods.

Keywords: Green Analytical Chemistry, White Analytical Chemistry, RGB color model.