ANALYTICAL METHODS FOR THE ESTIMATION OF FLUPIRTINE MALEATE IN BULK AND IN FORMULATIONS
M. Rama Krishna*, Dr. J. N. Suresh Kumar, B. Mounika, Ch. Praveen, Ch. Sanjana, M. Jhonson and P. Rajesh
ABSTRACT
The medicine Flupirtine maleate is a non-opioid analgesic with a central action, belongs to the cure class. It's included in the chemical emulsion known as ethyl 2- amino- 6 (4 flurobenzyl) amino pyridine-3-carbamate. It seems to serve by stimulating descending monoaminergic pathway in the brain and spinal cord which suppresses the transmission of the pain experience to those regions. It acts on the noradrenaline. Flupirtine not only reduces pain but also relaxes muscles via GABA- argic pathway and prevents seizures. This review composition presents the collection and discussion of colorful validated logical styles applied for the medicine Flupirtine maleate for confirmation, estimation, and quantification by using UV- Spectroscopy, Spectro fluorimetry, HPTLC, TLC and RP- HPLC, spectrophotometry for contemporaneous with paracetamol.
Keywords: Flupirtine maleate, UV-Spectroscopy, RP-HPLC, Spectro fluorimetry, HPTLC (High performance thin layer chromatography), TLC (Thin layer chromatography), Analytical methods.
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