CHARACTERIZATION AND EVALUATION OF ANTIPYRETIC ACTIVITY OF ALTERNANTHERA BRASILIANA (L.) KUNZTE ETHANOLIC LEAVES EXTRACT
Unnimaya I. S.*, Dr. G. N. Pramodini, Dr. D. Vijay Kumar and Dr. Sapna Shrikumar
ABSTRACT
Alternanthera brasiliana (L) Kuntze Amaranthaceae is A herbaceous plant used against inflammation, cough, and diarrhea in Brazilian popular medicine. It is a well-known plant rich in phytoconstituents. In the present work deals with the spectroscopic characterization and evaluation of in-vivo Antipyretic activity of ethanolic leaves extract of Alternanthera brasiliana (L) Kuntze. Spectroscopic analysis by FTIR revealed the presence of flavoids especially quercetin, through the appearance of intense bands at specific areas. Antipyretic activity of ethanolic extract of Alternanthera brasiliana (L) Kuntze leaves were evaluated using yeast induced pyrexia model. At the dose 200 mg/kg of ethanolic extract shows significant reduction in body’s temperature (p>0.05) was observed in the temperature of rats tested.
Keywords: Alternanthera brasiliana (L.) Kuntze, Flavonoids, Ethanolic extract, FTIR, Antipyretic activity.
[Full Text Article]
[Download Certificate]