EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

RETROSPECTIVE ANALYSIS OF RETINAL NERVE FIBRE LAYER THICKNESS ANALYSIS IN CASES OF POAG AFTER ADEQUATE IOP CONTROL IN CASES OF POAG

*Dr. Jyoti Kandagdla

ABSTRACT

Purpose: the study aims to investigate the retinal nerve fibre changes by utilizing Spectral domain Optical coherence tomography in cases of POAG after adequate IOP control. Methods: Retrospective analyses of all cases of primary open angle glaucoma between 2018 to 2020 were analyzed with respect to RNFL thickness and C: D ratio. The recordings of RNFL thickness and Optic nerve head changes as shown in the reports were analyzed using Zeiss 5000 spectral domain OCT machine. All reports with poor signal strength were discarded. Result: A total of 58 eyes of 32 patients of POAG were analyzed. Cases of other types of glaucoma were excluded. The serial OCT reports of the patients over a minimum period of 6 months were taken into consideration. The study showed that 33.89 percent of the cases showed more than 5 microns of increase in RNFL thickness. The rest either showed no changes or decrease in RNFL thickness. The improvement in the nerve fibre thickness was statistically significant. Conclusion: The above study gives evidence of resersibility of retinal nerve fibre thickness after adequate control of glaucoma leading to increase in nerve fibre thickness. This study gives hope of reversibility in glaucoma patient.

Keywords: primary open angle glaucoma, retinal nerve fibre thickness, glaucoma progression.


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