PATIENT ADHERENCE TO WARFARIN THERAPY AND ITS IMPACT ON ANTICOAGULATION CONTROL

Intisar Ahmed Ali Alhassan, Egbal Abbashar Algamar, Mohamed Idriss Yahia Musa and Omer Abdalgabar Musa Hassan*

ABSTRACT

Background: Medication adherence is crucial for the success of a therapeutic plan, especially in warfarin therapy. Objective: This study aimed to measure warfarin-adherence, and to identify their relation to the International Normalized Ratio. Methodology: This a descriptive cross-sectional hospital base study was conducted among patient who underwent long-term treatment with warfarin therapy. A study conducted in two cardiac hospitals at Khartoum State. Results: The study found that older individuals over 39 years had higher adherence levels than younger individuals under 39 years, and female participants had higher adherence levels than male participant. most participants had a current International Normalized Ratio within normal range, with 66.7% of high-level adherence having a current International Normalized Ratio in the normal range. However, the association between adherence and International Normalized Ratio results was insignificant. Therefore, most participants had a high level of adherence to warfarin therapy. Conclusions: Most participants have a normal International Normalized Ratio and a high level of adherence to warfarin therapy.

Keywords: Medication compliance, INR monitoring, Warfarin therapy, Patient adherence, and Dose adjustment.