INFLUENCE OF GREEN SYNTHESIZED AND CHEMICALLY SYNTHESIZED CERIUM OXIDE NANOPARTICLES ON FLEXURAL STRENGTH AND CANDIDAL ADHESION OF PMMA DENTURE BASE RESIN

Sushma K.V.*

ABSTRACT

Background and Objectives: Fracture of the dentures and denture stomatitis are the most common clinical scenarios of removable denture prosthesis. To overcome this Cerium oxide nanoparticles (nCeO2) of grain thickness 30-50nm were added in concentrations 0.75% and 1.5% by weight to PMMA denture base resin and its flexural strength and candidal adhesion were evaluated. Materials and Method: 100 samples were prepared with dimensions 65x10x3mm (ISO 1567). These samples were grouped into Group A1 and A2 (control groups) containing 10 samples each. Remaining 80 samples were divided into 8 groups according to the concentrations and method of synthesis of nCeO2. Group B1, Group C1, Group D1, Group E1 for flexural strength testing. Group B2, Group C2, Group D2, Group E2 for candidal adhesion testing. Samples were subjected to flexural strength and candidal adhesion testing according to their respective groups. Obtained values were analysed statistically using one-way ANOVA and Games- Howell’s test. Results: The mean flexural strength of the control group D1 was the highest (75.27 MPa) followed by group E1 (69.22 MPa), B1 (66.29 MPa), A1 (65.94 MPa) and least for C1 (62.52 MPa). For candidal adhesion, the least was seen with group E2 (0.0529) followed by group B2 (0.0653), C2 (0.0729), D2 (0.0843) and the highest for group A2 (0.1545). Conclusion: Increase in flexural strength and decrease in candidal adhesion for PMMA denture base resin was best noted with the incorporation of 1.5% wt. green synthesized nCeO2 of 30- 50nm grain thickness although higher flexural strength was noted with the incorporation of 1.5% wt. chemically synthesized nCeO2 of 30-50nm grain thickness it had higher candidal adhesion.

Keywords: Conventional PMMA; Cerium oxide nanoparticles; Chemical and Green synthesis; Flexural strength; crystal violet assay, Candida albicans.