ADVANCES IN TREATMENT MODALITIES FOR VITILIGO: A COMPREHENSIVE REVIEW OF EMERGING THERAPIES

Riya Ann Reji*, Satish S. and A. Ramakrishna Shabaraya

ABSTRACT

A chronic autoimmune disease called vitiligo is typified by skin that has lost pigmentation as a result of melanocyte death. It has a profound emotional impact and negatively impacts people's quality of life everywhere it affects people. The pathogenesis is a result of intricate interactions between environmental variables, autoimmune systems, and genetic predisposition. The goal of vitiligo management is to stop the disease's progression and cause the affected areas to repigment. Topical corticosteroids, phototherapy, and surgical procedures such autologous melanocyte transplantation are examples of conventional therapies. Novel approaches to the treatment of vitiligo have emerged, including cellular treatments, immunological regulation, and melanocyte stimulation. This review highlights current knowledge about the pathophysiology of vitiligo, traditional treatment choices, and upcoming new medicines and emerging therapies, emphasizing their efficacy, safety profiles, and potential future paths.

Keywords: Vitiligo, melanocyte stimulation, emerging therapies.