DEVELOPMENT AND EVALUATION OF ANTI-DIABETIC HERBAL FORMULATION

Kandagatla Sumanth* and Dr. A. Pavani

ABSTRACT

The Moringa Oleifera plant has various medicinal properties in each part of the plant. The leaves, stems, roots, and pods have medicinal properties that can enhance body functioning through regular intake in the diet. Moringa leaves contain flavonoids such as quercetin, isoquercetin, chlorogenic acid, and isothiocyanates, which have good anti-diabetic properties. This study aimed to formulate and evaluate Moringa Oleifera leaves tablets to treat type-II diabetes by wet granulation method. Moringa leaves are extracted by the maceration process. Extraction is carried out for 72 hours. The extract was dried by placing it in the water bath and stored for further use. Moringa leaf tablets were developed using a wet granulation technique. All formulations were evaluated by pre-compression and post-compression parameters like diameter, rigidity, weight variation, thickness, friability, disintegrating time, and dissolution rate. Invitro studies are performed. It may be concluded that the Moringa oleifera leaf tablets have good anti-diabetic properties and beneficial effects in treating Type-II diabetes.

Keywords: Moringa Oleifera, Quercetin, Chlorogenic acid, Invitro studies, Anti-diabetes.