EPIDERMODYSPLASIA VERRUCIFORMIS: A RARE CAESE PRESENTATION

Raj Kishor, Kumar Prateek*, Shrenik Balegar, Shyam Sundar Chaudhary, Shweta Kumari and Meena Rinoo Banwarilal

ABSTRACT

Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by a unique susceptibility to cutaneous infection by a group of phylogenetically related human papilloma viruses (HPVs). These patients show a defect in cell-mediated immunity specific toward the causative HPVs that lead to lifelong disease. The defect is usually inherited as autosomal recessive trait and presents clinically with plane warts, pityriasisversicolor-like lesions and reddish verrucous plaques. Dysplastic and malignant changes in the form of actinic keratoses, Bowen's disease and squamous cell carcinoma (SCC) are common but metastasis occurs rarely. A totally effective treatment against EV is as yet highly desirable. We report a case of epidermolysisdysplasiaverucciformis in a 13 year old female patient with confluent wart like lesions, pityriasisversicolor like lesions and reddish plaques. The case is being reported in view of rarity of disease.

Keywords: Epidermodysplasia verruciformis, genodermatosis, pityriasisversicolor.