VITAMIN E AND EPIGENETICS: IMPLICATIONS FOR HEALTH AND DISEASE

Nikita Chondhe*, Suresh Waghmare, Shiddhesh Chavan and Payal Durole

ABSTRACT

Vitamin E is typical component of numerous natural chemicals derived from plants and animals, including tocopherols and tocotrienols (α, β, γ, and δ). The promising results of these studies have made vitamin E a major area of study in the biomedical field, highlighting its additional beneficial properties, such as antibacterial, anti-inflammatory, and anti-cancer properties. The main lipid-soluble element of cells' antioxidant defense mechanism is vitamin E, which is exclusively found in food. Because of its antioxidant effect, it carries out several vital bodily activities. The human body prefers α-tocopherol, even though all eight of the vitamin E-related chemicals that are present in the diet are produced by plants and scavenge peroxyl radicals. Regulatory processes that help to preserve α-tocopherol and eliminate the non-α-tocopherol forms are crucial to vitamin E's biological activity. The biological significance of vitamin E and its uses in food packaging and cosmetics are well documented in the literature, and there are numerous reviews available. Our goal in this review is to highlight the most recent research on how vitamin E-rich antioxidant supplements affect exercise and athletic performance. This review's main goal is to clarify the molecular processes underlying AMD is a progressive and permanent degeneration of central vision that may be treated by vitamin E signaling pathways. The primary causes of cardiovascular issues are inflammation and the oxidation of the body's low-density lipoproteins. Future research should focus on pinpointing the precise genes or signaling pathways that vitamin E affects. Studies should concentrate on the impact of maternal vitamin E consumption on children's health and risk of disease, since vitamin E may influence fetal development through epigenetic programming.

Keywords: Tocopherol, Vitamin E, Health, Antioxidants.