EXPLORING AMLODIPINE- INDUCED GINGIVAL ENLARGEMENT: A CASE REPORT
Dr. Priya Swami*, Dr. Mona Shah, Dr. Vidhi Kevadia, Dr. Yogesh Doshi, Dr. Eesha Chidgupkar
ABSTRACT
Gingival overgrowth is a well-recognized adverse effect associated with phenytoin, cyclosporine, and calcium channel blockers. The exact pathogenesis of drug- induced gingival overgrowth remains unclear, and no single unifying hypothesis currently links these three commonly implicated drugs. Key factors influencing this model include age, genetic predisposition, pharmacokinetic variables, plaque-induced inflammatory and immunological responses, and activation of growth factors. A deeper understanding of the underlying mechanisms may pave the way for more effective strategies to manage and control this undesirable condition.
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