CUBOSOMAL DRUG DELIVERY SYSTEM -A REVIEW ON ITS EXCIPIENTS, METHODS OF PREPARATION AND EVALUATION
M. Sujitha and M. Sriram*
ABSTRACT
The review article covers the details of cubosomes. This novel drug delivery system, which are emerging as promising drug delivery system for the delivery of both hydroplilic and lipophlilic drugs. Cubosomes are lipid vesicles and it’s compared to vesicular system like liposomes. Cubosomes nanoparticles are look like dot square and slightly spherical in shape. Cubosomes are bicontinuous cubic liquid crystalline system formed by self-assembly of surfactants molecules. The present study of cubosomes as a drug carriers, excipients profile, mechanism of action, various techniques used in preparation of cubosomes, their evaluation and different application.
Keywords: Cubosomes, Liquid crystal, Honeycomb, glyceryl mono oleate[GMO], poloxamer 407.
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