REVIEW OF DIOSGENIN AND ITS PHARMACOLOGICAL EFFECTS
Aditi Rajaendra Waghmare*, Astikta Ashok Bhondave, Dr. Hemant V. Kamble and S. R. Ghodake
ABSTRACT
Diosgenin is a steroidal sapogenin, which has been proven to have various pharmacological effects such as anti-cancer, anti diabetic, anti-inflammatory,immune system modulating effects, anti-thrombotic, antiasthmatic, hepatoprotective, anti-atherosclerosis, hypolipidemia and antioxidative and neuroprotective effects. This review is to summarize the sources, Bioavailability and Pharmacokinetic Studies,it shows promising pharmacological effects of diosgenin, clinical studies investigations have demonstrated diosgenin’s nontoxic nature and Toxicological Profile in which the discuss the Safety profile of diosgenin. Aiming to provide detailed information for the further development and application of diosgenin, which is important to improve the utilization value of diosgenin.
Keywords: Diosgenin(DG), steroidal sapogenin, Pharmacological effects, safety profile.
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