THE ACNE VULGARIS GEL AND IT’S TREATMENT: A REVIEW

Radhe Omar* and Arun Pratap Singh

ABSTRACT

A prevalent long-term inflammatory disease that affects the pilosebaceous follicles worldwide is acne vulgaris. Its intensity may cause pain, scars, and significant psychological effects, including depression, even though it is not life-threatening. The several causes of acne and the remedies for them are examined in this article. It also covers new dosage formulations, existing drugs, and findings from ongoing clinical studies. Four main aspects contribute to the pathophysiology of acne: inflammation, hyperproliferation of Propionibacterium acnes (P. acnes), hyper keratinization of pilosebaceous follicles, and excessive sebum production. Effective diagnosis and treatment of Acne vulgaris relies on accurately identifying acne lesions, including both non-inflammatory (blackheads and whiteheads) and inflammatory (papules, pustules, nodules, and cysts). This review briefly discusses traditional acne treatment approaches, including topical treatments (such antibiotics and retinoids), systemic treatments (including hormone medications, antibiotics, and retinoids), and physical treatments. It also discusses the difficulties caused by P. acnes's resistance to antibiotics that are often found in brand-name drugs, highlighting the need of innovative treatment approaches. Lastly, we look at cutting-edge commercial drugs and new acne therapies that are now undergoing clinical testing.

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