EFFICACY OF CURCUMIN AGAINST GASTRO-INTESTINAL PARASITES IN GOAT

†Fahmida Afrin, *†M. M. R. Chowdhury, S. S. Saha, Md. Ataur Rahman, Md. Ali Asgar, Md. Kamrul Islam

ABSTRACT

A total of 30 Black Bengal goats weighing (11-19 ± 2.6) kg irrespective of sex infested with gastrointestinal parasites were selected for this experiment and were randomly assigned into one of three equal groups (n =10) A(control), B (0.2% curcumin with normal ration) and C (0.6% curcumin with normal ration) with free access to food and water for 60 days. The body weight increased in some cases by the treatment with the advancement of age but statistically insignificant. The highest body weight was found in the group C. The eosionphil count of group B and C decreased significantly (p<0.05) compared to control. At the end of experiment the lowest eosinophil count was observed in the group C but at the beginning of the experiment, it was the highest. The fecal egg count of Paramphistomum worm in group C was significantly higher than others (p<0.05). In control group the rate of infestation were increased (Akanda et al., 2012) but at the 60th day of the experiment the fecal egg count in all group is significantly lower (p<0.05). The egg count of Haemonchus sp. and Strongyles was insignificant throughout the experiment. No characteristic lesion has been identified in the gastro-intestinal mucosa but gastritis with infiltration of inflammatory cells in the sub mucosa and in the liver parenchyma showing coagulation necrosis in the hepatocytes around the central vein and slightly swollen hepatocytes of the control animals as well as 0.6 % curcumin fed animals.

Keywords: Curcumin, Paramphistomum sp., Fasciola sp., Haemonchus sp., Strongyles.