AN OBSERVATIONAL STUDY, PREVALENCE OF CANDIDA SPECIES IN CATHETER ASSOCIATED URINARY TRACT INFECTION IN ICU PATIENTS AT A TERTIARY CARE HOSPITAL AT INDORE MADHYA PRADESH, INDIA

Vipul Mathur*, Madhurendra Rajput and Shiwani Mathur

ABSTRACT

Introduction: Catheter associated urinary tract infection (CAUTI) is most common nosocomial infection which constitutes ~80% of nosocomial urinary tract infections (UTIs). candida species have emerged as an increasingly important of cause of infection This observational study, aimed to investigate the prevalence and species distribution of candida infections in catheter associated urinary tract infection among ICU patients at a tertiary care hospital at Indore Madhya Pradesh, India. Material and Methods: A cross-sectional prospective observational study carried out over a period of 18 month from Jan 2018 to June 2019. Total 350 urine sample were collected during our study and were analyzed on the basis of inclusion and exclusion criteria. Before starting the study, ethical approval was obtained from the Institutional Ethics Committee. Results: In this study 350 urine sample were collected and analyzed. Out of these 350 urine samples; Yeast growth (Candida species) was obtained in 71(20.28%) urine samples. Over all 71 Candida isolates, among them 39 (54.92%) were female and 32 (45.07%) were male. The maximum number of patients were found to be 41-60 years of age group. Out of 71 Candida isolates; Non albicans Candida (NAC) were 45(63.38%) and Candida albicans were 26 (36.61%). (Shown in figure 4) The prevalence of non- albicans Candida spp. was much higher than the Candida albicans species. Conclusion: Our study, we conclude that the increasing burden of Candida associated CAUTI is causing large burden to both the healthcare system. It also Changing pattern of Candida species causing UTIs around the world points towards continuous need for surveillance, thus helping us in providing appropriate therapy.

Keywords: Candida Albicans, Non albicans Candida (NAC) , Urinary Tract Infections (UTIs). Intensive Care Unit (ICU).