EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

LITERATURE REVIEW ON BIOLOGICAL ACTIVITY OF NOVEL 2-SUBSTITUTED BENZIMIDAZOLE SCHIFF’S BASES AND ITS AZETIDINONE AND THIAZOLIDINONE DERIVATIVES

Dr. Abhay Kumar Verma*, Dr. Arun Kumar Singh (Sr.), Priyanka Shrivastav, Ranjeet Kumar Bhargav, Rehana Parveen and Vijay Kumar Gupta

ABSTRACT

The Benzimidazole ring is an omnipresent structural feature of many synthetic compounds with diversified therapeutic efficacy. A large volume of published literature over the last few decades on 2-substituted benzimidazole Schiff’s bases derivatives preludes a comprehensive review. The major activities exhibited by the 2- substituted benzimidazole Schiff’s bases derivatives are, antibacterial, antifungal, antiviral, anti-tubercular, analgesic, anti-inflammatory, anti-helminthic, sedative, hypnotic, anticonvulsant etc. The article presents a comprehensive review on the biological activities of some novel derivatives of 2-substituted benzimidazole Schiff’s bases.

Keywords: Benzimidazole, Schiff’s base, antibacterial, analgesic, anticonvulsant.


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SJIF Impact Factor: 7.065

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