MULTICENTRIC RETICULOHISTIOCYTOSIS: A COMPREHENSIVE CASE REPORT

Naqsh Thakur*, Yogita Bhansali and Tapsh Thakur

ABSTRACT

Multicentric reticulohistiocytosis (MRH), previously known as lipoid dermatoarthritis, is a rare systemic disorder characterized by cutaneous nodules and progressive polyarthritis. It primarily affects middle-aged women and can lead to joint destruction and deformities resembling rheumatoid arthritis. The etiology remains unclear, with possible associations with malignancies and autoimmune diseases. We present a case of a 52-year-old woman with multiple skin nodules and severe polyarthritis, leading to a diagnosis of MRH based on histopathological and immunohistochemical findings. Early diagnosis and intervention were critical in managing symptoms and preventing joint damage. This report highlights the diagnostic challenges and therapeutic options available for this rare condition.

Keywords: .