RECENT ADVANCES IN NANOSPONGES AS DRUG DELIVERY SYSTEM: A REVIEW ARTICLE

Divya Singh*, G.C. Soni and S.K. Prajapati

ABSTRACT

Topical drug delivery system faced many problems like poor permeability, skin irritation, allergic reactions etc. The new developed colloidal system called nanosponge has potential to overcome these problems. Nanosponges are tiny sponges with a size of about a virus (250nm-1μm), which consist of cavities that can be filled with a wide variety of drugs. Nanosponge play vital role in targeting drug delivery in a controlled manner. Both lipophilic and hydrophilic drugs are incorporated in nanosponge. The outer surface is typically porous, allowing controlled release of drug. They enhanced solubility, bioavailability reduce side effects and modify drug release. Nanosponge drug delivery system has emerged as one of the most promising fields in pharmaceutics.

Keywords: Nanosponge; Topical Delivery; Controlled Release.