THE GENDER-AGE FEATURES OF PREVALENCE OF THE RISK FACTORS IN THE PATIENTS WITH SHARP CORONARY SYNDROME/ACUTE MYOCARDIAL INFARCTION BY THE DATA OF THE REGISTER IN ONE OF THE REGION OF TASHKENT.

Urinov O.*, Mamutov R. SH., Abidova D. E. and Mamrajapova D.A.

ABSTRACT

In Uzbekistan there has been noted the growth of morbidity and mortality because of cardio-vascular diseases (CVD) over the last two decades and the structure of the common mortality does not differ from the world: cardio-vascular diseases are also the most important cause of the death[1,2,3]. The increase of morbidity and referrals to the doctors (the quantity of the registered patients) due to CVD ( from 1410,0 to 2228,7 and from 7200,5 to 7541,5) заболеваемости and morbidity (i.e. quantity(amount) of the registered patients) from ССЗ (according to 1410,0 up to 2228,7 and with 7200,5 up to 7541,5, respectively) in 2004 -2009 indicates about activation of the identification and taking into account of the patients with cardio-vascular pathology[4]. The development of ACS/AMI is accompanied by high frequency of cases of hospital death and not fatal cardiovascular complications, the leading role in which development is allocated to the risk factors (RF) not only to separate, but also to their associations, especially, that potentiates an opportunity of the development of disease and its outcome in dependence on the number of RF. It is important also, that the potential of each RF may have regional differences. The concept of risk factors (RF), based on the results of started in 1948 Framingham heart study is a scientific basis of prevention of the cardiovascular diseases (CVD)[5,6,7]. In this research has been revealed that the main risk factors of CVD of atherosclerotic genesis are presented by arterial hypertension (AH), hypercholesteremia (HCS), smoking, obesity, diabetes mellitus (DM) and low level of physical activity, and also high level of triglycerides in the blood and low level of cholesterol of high density lipoproteins, age and gender. These main risk factors of CVD, forming the total risk and influencing on the prognosis, may be determined at the relatively simple screening observation with use of standard methods of examinations[8]. In the numerous epidemiological studies there has been proved that performance in time of preventive measures in the relation of RFs can reduce morbidity and mortality due to CVD[9,10]. Purpose. To study the gender-age features of the prevalence of risk factors (RF) in the patients with ACS/AMI on the basis of the register in one of the regions of Tashkent. Material and methods. The data from cohort prospective study “Register of acute myocardial infarction and acute coronary syndrome in one of the regions of Tashkent” were the basis for present study. ACS and AMY were studied among the constant population in one of the regions of Tashkent with analysis of the following documentation: the date of the “03” service, medical histories and extracts from case reports, ambulatory cards from the polyclinic histories of illnesses and extracts from стационара, out-patient maps from polyclinic, protocols of openings, certificates from the service of forensic medicine, certificates of death from the municipal registration system. There were used populational-preventive, statistic, mathematic methods with calculation of the criteria χ2 and Mac-Nimar for determination of the reliable differences of the qualitative parameters. Results. The risk factors of ACS/AMI were found in 683 (100%) of patients, including 1 RF – in 40(5,8%) patients, 2RF – in 129(18,9%), 3RF – in 21831,9%), 4RF – in 147(21,5%), >5 – in 149 (22,0%). Arterial hypertension was on the first place – 81,7%, increased BMI – on the second place -81,2%, smoking – on the third – 44,5%, hypercholesteremia (HCS) – on the fourth -37,5%, DM – on the fifths place -32,5%.

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