EVALUATION OF PROLACTIN, TESTOSTERONE AND FOLLICLE STIMULATING HORMONE OF SUDANESE MALES WITH VARICOCELE ATTENDING AN INFERTILITY CLINIC

Eltayeb Tayrab* and Bedawi Sayed Bedawi

ABSTRACT

Varicocele is observed in 19–41% of men with infertility it has been associated with hormonal imbalance and testicular hyperthermia. The objective of this study was to assess the serum levels of prolactin, testosterone and follicle stimulating hormone (FSH) among 186 men with varicocele attending andrology clinic in Reproductive Health Care Center (RHCC) Khartoum Sudan, beside 52 normal age matched fertile men as control group. Automated chemical analyzer was used to measure these hormones. The mean serum prolactin in varicocele group was (269.66±20.03 ng/ml), versus (185.79 ±9.77 ng/ml); P value (0.006), testosterone was (14.04±0.44 ng/dl), versus (14.54±0.75 ng/dl) and FSH (11.41±0.96 mIU/ml), versus (5.18±0.39 mIU/ml); P value (0.003). The study illustrated a significant increase in serum prolactin and FSH in the test group compared to the control group. Conclusion: in Sudanese men with varicocele serum prolactin and FSH significantly increase; while serum testosterone does not significantly change.

Keywords: Varicocele, infertility, serum, prolactin, testosterone and follicle stimulating hormone.