ASSESSMENT OF HYPERFIBRINOGENEMIA IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION FOR A POSSIBLE RISK FACTOR

P. Murugesan* and L. Madhan

ABSTRACT

Hyperfibrinogenemia is a condition where increase in plasma fibrinogen level was observed. The present study was aimed to assess the plasma fibrinogen level in patients with acute myocardial infarction. The study also focuses on the relation of plasma fibrinogen level to the etiology and prognosis of acute myocardial infarction. A group consisted of 50 patients in the age group of 40-65 years diagnosed with myocardial infarction associated with various risk factors were taken for the study. Rapid turbidimetric method was adopted for the estimation of fibrinogen. Uniform elevation of plasma fibrinogen was observed in patients with acute MI regardless of age, sex and other risk factors. The study results revealed that hyperfibrinogenemia is an important risk factor of acute MI and hence routine clinical investigations and measurement of plasma fibrinogen concentration may be carried out in patients with acute MI.

Keywords: Fibrinogen, hyperfibrinogenemia, acute myocardial infarction, risk factor.