EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

ANTIMICROBIAL IN VITRO PHARMACOLOGICAL STUDIES OF SOME PYRAZOLYL QUINAZOLIN-4(3H) ONE DERIVATIVES

Gaman G. Barat*

ABSTRACT

Some pyrazolylquinazolin-4(3H) one derivatives were synthesized by the base catalysed cyclisation of acrylamide with 3:5-dinitrophenyl hydrazine hydrate. The overall reaction was carried out by multistep process. The structural confirmation of the synthesized compounds was carried out on the basis of elemental analysis, IR and NMR spectra results. The title compounds were screened for antibacterial and antifungal pharmacological studies in vitro by cup plate method. The potency of synthesized compounds focus on the strength compared with standard drug.

Keywords: Antibacterial, Antifungal, Acrylamide, Quinazolin-4(3H) one.


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SJIF Impact Factor: 7.065

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia

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