TO EVALUATE THE ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC LEAF EXTRACT OF MORINGA OLEIFERA PLANT IN ALBINO WISTAR RATS

Shaikh Alimuddin* and V. N. Bonde

ABSTRACT

Introduction : Moringa Oleifera is widely found in Asian subcontinent and it has been used as an analgesic and anti-inflammatory in Indian folk medicine. In this study we compared the antiinflammatory effects of Moringa Oleifera Ethanolic extracts in experimentally Carrageenan induced model of inflammation in rats. Material and methods: A total of 30 Male Albino Wistar sex weighing 150-200g (n= 30) were used. Ethanolic extracts of Moringa Oliefera Leaf [eemo] were prepared with the help of soxhlet’s apparatus. The anti-inflammatory activity was studied using carrageenan induced paw edema method . statistical analysis was performed using one-way analysis of variance (Anova) followed by post hoc dunnett’s test. P < 0.05 was considered statistically significant. Results: In carrageenan induced paw edema method, moringa olefera treated groups demonstrated dose dependent decrease in paw edema compared to control group. Conclusion: We can be conclude that the Ethanolic Extracts of Moringa Oleifera Leaf possesses anti-inflammatory activity.

Keywords: Moringa Oleifera, Carrageenan, Anti-Inflammatory.