A RARE CASE OF HYPOFIBRINOGENEMIA

Dr. Shyam Srinivasan*, Dr. Devanand Gulab Chaudhari, Dr. Prachi Atmapoojya, Dr. MD. Sabri Ahsan

ABSTRACT

Afibrinogenemia is a rare bleeding disorder with a estimated prevalence of 1 in 10,00,000.[1,2] It is a autosomal recessive disorder resulting from mutation of any of the 3 genes that encodes the 3 polypeptide chains of the fibrinogen and are located on the long arm of chromosome 4.[3] Afibrinogenemia is often diagnosed at birth following prolonged umbilical cord bleeding and is characterized by spontaneous bleeding in all tissues, while hypofibrinogenemic patients are more often asymptomatic.[4] Here by we present a case of Hypofibrinogenemia in a 2 year old female child who had repeated episodes of bleeding following a minor trauma to the oral cavity.

Keywords: Afibrinogenemia, Hypofibrinogenemia.