TREATMENT OF LIVER DISEASE BY HERBAL DRUGS

Zeashan Hussain, *Raziuddin Khan, Vikash Kumar Chaudhari and Sunil Jawla

ABSTRACT

It is very interesting to note that there is no drug available in the modem system of medicine for treating hepatic disorders; only certain herbal preparations are available to treat this quite vulnerable disease. Several hundred plants have been examined for use in a wide variety of liver disorders. Just handfuls have been fairly well researched. The latter category of plants include Silybum marianum (milk thistle), Picrorhiza kurroa (kutkin), The standardized aqueous extact of Glcyrrhiza glabra (Stronger Neo-Minophagen C) has to be administered parenterally (80 gram, daily) can normalize aspartate transaminase and alanine transaminase in over 60% of the patients. Hepatoprotective activity of Emblica officinalis and Chyavanaprash extracts were studied using carbon tetrachloride induced liver injury model in rats, both extracts were found to inhibit the hepatotoxicity produced by acute chronic CCl4 adminstration has seen from the decreased levels of serum and liver lipid peroxides (LPO), glutamate-pyruvate transaminase (GPT), and alkaline phosphate (ALP).

Keywords: Liver disease, Herbal drugs, Hepatoprotective activity.