“A CLINICO-MICROBIOLOGICAL STUDY OF TUBERCULOSIS IN IMMUNOCOMPROMISED AND IMMUNOCOMPETENT PATIENTS”

N. S. Brahme, D. Majumdar*, S. Chakraborty, A. Naskar, M. K. Ghosh, S. Mallik and B. Saha

ABSTRACT

Tuberculosis is a widespread, fatal disease caused by Mycobacterium tuberculosis. Tuberculosis typically involves the lungs, but can affect other parts of the body. One-third of the world's population is thought to have been infected with M Tuberculosis with new infections occurring in about 1% of the population each year. More people in the developing world contract tuberculosis because of a poor immune system, largely due to high rates of HIV infection. The current worldwide estimate of the number of cases of HIV infection among adults are 38.6 million, one third of them co-infected with M tuberculosis. Our study showed pleural effusion was the most common presentation in nonHIV group where as cervical lymphadenopathy in HIV group with no difference in occurrence of INH/Rifampicin resistance. There is no statistical difference of sputum positivity in AFB between the groups and without significant correlation of CD4 count among HIV group.

Keywords: HIV, EPTB, Respiratory tract.