CARVEDILOL MORE THAN MERE A BETA-BLOCKER

Dr. Ananda Kumar. Chettupalli*, Narender Boggula, Eslavath Ravindar Naik, Dr. B. Vasudha

ABSTRACT

Carvedilol is a cardiovascular drug of multifaceted therapeutic potential, with beta-blocker and vasodilatative activity. These actions confer to the above mentioned beta blocker some beneficial properties on several processes involving cardiovascular system. Carvedilol provides hemodynamic, ant ischemic, anti-proliferative and antiarrhytmic benefits, for its antioxidant neuro humoral and electrophysiological effects. All these actions provide the basis for usefulness of the drug in the treatment of hypertension, coronary heart disease, and congestive heart failure. In this review we report the beneficial properties of Carvedilol and we analyze the rational clinical use of this beta blocker taking special attention on recent clinical trial in heart failure where it appears evidence supporting an important, favorable effect of the drug.

Keywords: Carvedilol, Hypertension, Coronary disease, Hearth failure.