ETHOSOMAL GEL: A REVIEW

Nimmy Johny K.*, Krishnakumar, Dineshkumar B. and Smitha K. Nair

ABSTRACT

Ethosomal systems are lipid vesicular carriers which containing high percentage of ethanol. These nanocarriers are formulated to overcome the limitations associated with conventional oral therapy. Which deliver drugs into deep skin layers. Different preparation techniques are used in the preparation of these nanocarriers. For patient compliance and stability, ethosomal dispersions are incorporated in to gels, patches, and creams. This publication gives a detailed review on the effects of ethosomes, constituents, mechanism of drug penetration, formulation methods, evaluation and examples for drugs used in ethosomal systems.

Keywords: Ethosomes, Transdermal drug delivery, Lipid vesicular systems, Gel.