STANDARDIZATION OF PHYTOTHERAPEUTIC CONSTITUENTS IN AYUCEE PREMIX

Kotagiri Ravikanth#, Anil Kanaujia*, Deepak Thakur, Anirudh Kumar Sharma, Uday Veer Singh

ABSTRACT

Lack of proper standard parameters for herbal preparation and several instances of substandard herbs, adulterated herbs have come into existence and thus it becomes imperative to standardize the polyherbal formulation to ensure the batch to batch consistency in quality of product and its efficacy. As pharmacological properties of an herbal formulation depend on phytochemical constituents present therein, development of authentic analytical methods which can reliably profile the phytochemical quantification to maintain reproducible efficacy and safety of phytopharmaceutical is paramount responsibility of herbal drug industry. Standardization of the product Ayucee premix with respect to its phytotherapeutic constituents was undertaken and new validated HPTLC methods were developed for the quantification of two of its bioactive phytoconstituents.

Keywords: HPTLC, Gallic acid, Ursolic acid, Ayucee premix.