CEREBRAL TOXOPLASMOSIS IN PATIENT WITH ACQUIRED IMMUNODEFICIENCY SYNDROME: A CASE REPORT

Rameshwari Bithu, Romika Dawra* and Rakesh Maheshwari

ABSTRACT

Introduction: Cerebral toxoplasmosis commonly affects patients with advanced HIV immunodeficiency which can be severe and debilating and condition may be fatal. We report the case of 30 yr old male who was known case of HIV, presented to our institute with complaints of fever (not associated with chills & rigors), urinary incontinence & altered sensorium. MRI scan of his brain showed peripheral enhancement in bilateral basal ganglia and thalamia, in bilateral cerebral and right cerebellar hemisphere with moderate perilesional edema. Toxoplasma serology revealed raised IgG antibody levels. He was treated with cotrimoxazole DS, clindamycin & pyrimethamine. The patient was symptomatically better after 72 hrs. Conclusion: Disseminated toxoplasmosis is a major health problem in immunocompromised patients & is necessary to examine patients before, during & after chemotherapy for toxoplasmosis.

Keywords: perilesional edema, cotrimoxazole DS, immunocompromised.