AN OVERVIEW ON SUPERDISINTEGRANTS: A REVIEW

Jyoti Verma*, Dr. S. K Prajapati and Dr. R Irchhiaya

ABSTRACT

Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. The demand for fast disintegrating tablets, capsule has been growing during the last decade especially for geriatric and pediatric patients because of swallowing difficulties. Nowadays several newer agents have been highly-developed identified as Superdisintegrants. Superdisintegrants are the ingredients, which facilitate the quicker disintegration with lesser quantity in compare to disintegrants. Their demand is progressively increasing. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast- dissolving tablets. Here in this review article we are going to overview about of various disintegrates like natural, synthetic, co-proceed. The present review comprises the various kinds of Superdisintegrants like natural and synthetic which are being used in the formulation to provide the safer, effective drug delivery with patient's compliance.

Keywords: Disintegratants, Disintegration, Superdisintegrating agent.