ESTIMATION OF ESR AND BMD T-SCORE ON TREATMENT OF CISSUS QUADRANGULARIS LINN AND ZINGIBER OFFICINALE ROSC IN OSTEOARTHRITIS PATIENTS

J. Viswanath, S. Sankaraiah*, Renu Dixit, Chakrapani Cheekavolu, M. Naresh Kumar, Simhadri V. S. D. N. A. Nagesh and P. Leela

ABSTRACT

Background: Osteoarthritis represents a major cause of morbidity, disability and social isolation, especially where the hip and knee are involved. The classification and nomenclature of osteoarthritis are problematic and the multifactorial nature of osteoarthritis is well recognised. Methods: Total 60 patient‟s data was collected in S.V Ayurvedic Medical College and Hospital. Estimation of Erythrocyte sedimentations rate (ESR) and T-Score levels are before and after treatment of tested drugs in osteoarthritis patients. Treatment groups were: Group-A: Cissusquadrangularis linn-5 gm; Group-B: Zingiber officinale rosc-5 gm; Group-C: Cissusquadrangularis linn+ Zingiber officinale rosc-5 gm, all groups are twice a day orally with luke warm water. Results: Before and after treatment of tested drugs reduction in ESR was observed as follows (mean ± SD) Group A: 59.85 ± 22.013 to 14.25 ± 3.291 (p< 0.0001); Group B: 66.5±18.495 to 15.5±4.310 (p<0.0001); and Group C 71.85±19.543 to 17.1±5.609 (p< 0.0001). Before and after treatment of tested drugs increase in BMDT-Score was observed in all three groups as follows (mean ± SD) Group A: -1.33±1.057 to -1.29±1.073 (p<0.001); Group-B: -1.525±1.301 to -1.410±1.304 (p<0.001); Group C:-1.390±1.389 to 1.235±1.361 (p<0.0001). Conclusion: Present study reveals that improvement in terms of reduction in ESR was observed in all tested groups and improvement in terms of increase in BMD T-score was observed in all three groups.

Keywords: Osteoarthritis, ESR, BMD T-score, South India.