SYNTHESIS OF SOME NEW 2, 5 - DISUBSTITUTED THIADIAZOLE DERIVATIVES AND THEIR SCREENING FOR ANTIMICROBIAL ACTIVITY

Rabindra Khadka, Sushma Singh, Bikram Behera, Mrutyunjaya Bhanja and Chaitanya Prasad Meher*

ABSTRACT

Synthesis & screening of thiadiazole derivative has a great interest to numerous because of its easy accessibility and diverse biological properties. Thiadiazole derivatives have huge number of proven records of biological activities preferred in earlier discussions. So it was planned to synthesize a variety of 2,5-substituted thiadiazoles derivatives to provide an empirical approach towards, development of potent functional molecules possessing wide range of biological property, such as anti-microbial activity.

Keywords: Aromatic compound, Antimicrobial, Thiadazole nucleus, Pathogens.