STUDY OF THE BIOLOGICAL EFFECTS OF AN AQUEOUS MYRCIA RACEMOSA EXTRACT ON BACTERIAL CULTURES IN THE PRESENCE AND ABSENCE OF STANNOUS CHLORIDE SOLUTION.

Silva M. S., Nascimento C. C. H. C., Camacho A. C. L. F., Souza M. C., Oliveira J. F. F., Nascimento S. F., Vasconcelos S. D. D. De, Nogueira R. I., Diré G. F.,* and Barreto A. S.*

ABSTRACT

The species Myrcia racemosa (O.Berg) Kiaersk.is a phanerogamic plant belonging to the Myrtaceae family. Most drugs have numerous side effects that may restrict their use. An alternative to such medicinal products are medicinal plants, which offer an important perspective in the identification of bioactive compounds. The National Relation of Medicinal Plants of Interest to the SUS (Renisus) has the purpose of guiding studies and researches that may subsidize the elaboration of a list of medicinal and phytotherapeutic plants, to be made available for use by the population, with safety and efficacy for the treatment of disease. This study aimed to verify the action of an aqueous Myrcia racemosa extract in bacterial cultures in the presence and absence of the stannous chloride reducing agent. The extract was prepared from the infusion, filtered and subjected to refrigeration. To evaluate the cytotoxicity, we used the disc diffusion method in nutritive agar medium. After standardization of the turbidity of the saline solution (0.9% NaCl), to determine the CFU, it was compared with the 0.5 Mc Farland scale, after which the bacterial growth was evaluated in relation to the disks, which were impregnated with different volumes of SnCl2 solution and / or with a volume of 12 μL of the vegetal extract. The results suggest that the aqueous extract of Myrcia racemosa has redoxi property in relation to the observed cytotoxic and antioxidant effects. This study reports, for the first time, the biological effects of this extract.

Keywords: Myrcia racemosa, antioxidant, bactericidal, cytotoxic, stannous chloride.