PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF ALKALOIDS EXTRACT OF SENECIO CHRYSANTHEMOIDES

Darshan Singh*, S. C. Sati and Maneesha Dobhal Sati

ABSTRACT

The development of bacterial resistance to presently available antibiotics has necessitated the search for new antibacterial agents. The present work focuses essentially on the phytochemical and antibacterial screening of Senecio chrysanthemoides. The results revealed the presence of some chemical groups such as flavonoids, terpenes, alkaloids and saponins. The crude alkaloid extract was evaluated for their antimicrobial activity against four bacteria by the disc diffusion assay. The findings showed a broad spectrum of activity according to the following order in the sensitivity as indicated by the corresponding inhibition zone diameters: Escherichia coli > Salmonella typhimurium> Staphylococcus aureus> Pseudomonas aeruginosa.

Keywords: Senecio chrysanthemoides, phytochemical Screening, antibacterial activity.